Putaminal Recombinant Glucocerebrosidase Delivery with Magnetic Resonance-Guided Focused Ultrasound in Parkinson's Disease: A Phase I Study.
Ying MengChristopher B PopleYuexi HuangRyan M JonesJulie OttoyMaged GoubranLais Machado de OliveiraBenjamin DavidsonLiam S P LawrenceAngus Z LauAllison BethunePejman MaralaniAgessandro AbrahaoClement HamaniKullervo HynynenSuneil K KaliaNir LipsmanLorraine V KaliaPublished in: Movement disorders : official journal of the Movement Disorder Society (2022)
Results from this study demonstrate the safety and feasibility of MRgFUS GCase delivery in PD and support further investigation of this approach. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.