Epigenome-wide association studies in asthma: A systematic review.
Ahmed EdrisHerman T den DekkerErik MelénLies LahoussePublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2019)
Although many differentially methylated CpGs in genes known to be involved in asthma have been identified in EWAS to date, we conclude that further studies of larger sample sizes and analyses of differential methylation between different phenotypes are needed in order to comprehensively evaluate the role of epigenetic factors in the pathophysiology and heterogeneity of asthma, and the potential clinical utility to predict or classify patients with asthma.