Drug-drug interaction potential in men treated with enzalutamide: Mind the gap.
Guillemette Emma BenoistInge M van OortStella SmeenkAdrian JavadDiederik M SomfordDavid Marinus BurgerNiven MehraNielka P van ErpPublished in: British journal of clinical pharmacology (2017)
A high prevalence of potential DDIs was found. The inclusion and grading of potential DDIs was highly variable between the three drug interaction compendia. Physicians, nurses and pharmacists should be aware of this potential problem, which might require intensive monitoring or alternative treatment strategies to prevent suboptimal treatment of the co-morbidities in patients treated with enzalutamide.