Astrocyte elevated gene-1 participates in the production of pro-inflammatory cytokines in dental pulp cells via NF-κB signalling pathway.
H WuMiao HeR YangY ZuoZ BianPublished in: International endodontic journal (2018)
Astrocyte elevated gene-1 participated in inflammatory cytokine synthesis via NF-κB signalling in the dental pulp. Both NF-κB and PI-3K signalling are involved in LPS-induced AEG-1 expression in dental pulp cells.
Keyphrases
- lps induced
- induced apoptosis
- inflammatory response
- signaling pathway
- cell cycle arrest
- oxidative stress
- pi k akt
- nuclear factor
- copy number
- genome wide
- endoplasmic reticulum stress
- gene expression
- cell death
- immune response
- toll like receptor
- dna methylation
- transcription factor
- anti inflammatory
- genome wide analysis