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Sex and oestrogen receptor β have modest effects on gene expression in the mouse brain posterior cortex.

Jasmine A FelsGabriella A CasalenaGiovanni Manfredi
Published in: Endocrinology, diabetes & metabolism (2020)
Overall, our results suggest that in the adult mouse posterior cortex there are surprisingly few sex differences in gene expression, and those that exist are mainly related to cation channel activity. Additionally, they indicate that brain region-specific functional effects of ERβ may be largely post-transcriptional.
Keyphrases
  • gene expression
  • functional connectivity
  • resting state
  • dna methylation
  • cerebral ischemia
  • transcription factor
  • young adults
  • binding protein
  • endoplasmic reticulum
  • heat shock