Ion channel Piezo1 activation aggravates the endothelial dysfunction under a high glucose environment.
Xiaoyu ZhangShaoqiu LengXinyue LiuXiang HuYan LiuXin LiQi FengWei GuoNailin LiZi ShengShuwen WangJun PengPublished in: Cardiovascular diabetology (2024)
In summary, our study revealed that Piezo1 is involved in high glucose-induced oxidative stress injury and aggravated endothelial dysfunction, which have great significance for alleviating endothelial damage caused by hyperglycemia.