Aflibercept clearance through the drainage system in a rat model.
Yariv KeshetOrly Gal-OrMichal Schaap FoglerKarin MimouniMeydan Ben IshaiDov WeinbergerAssaf DotanPublished in: International journal of retina and vitreous (2021)
In our rat model, a complete clearance of Aflibercept from the anterior chamber angle, was seen 48 h after the injection. This finding refutes the theory of possible connection between IOP elevation and mechanical obstruction. Evacuation time of Aflibercept through the angle is of the same magnitude as that of Bevacizumab in the same rat model.