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Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study.

Gongbu PanSteve Simpson YapIngrid van der MeiJac C CharlesworthRobyn LucasAnne-Louise PonsonbyYuan ZhouFeitong WuBruce V Taylor
Published in: Journal of neurology, neurosurgery, and psychiatry (2016)
These data strongly suggest that MS genetic risk variants significantly influence MS clinical course and that this effect is polygenic.
Keyphrases
  • multiple sclerosis
  • copy number
  • mass spectrometry
  • genome wide
  • ms ms
  • white matter
  • electronic health record
  • big data
  • dna methylation
  • gene expression
  • machine learning