First total synthesis of asperilactone B. Revision of absolute stereochemistry of asperilactones B and C.
Sanja DjokićGoran BenedekovićJelena KesićMarko V RodićMirjana PopsavinVelimir PopsavinJovana FrancuzPublished in: Organic & biomolecular chemistry (2024)
The first total synthesis and absolute configuration assignment of asperilactone B (I) have been accomplished. Additionally, a revision of the absolute stereochemistry of asperilactone C has been done. The first total synthesis of the opposite enantiomer of asperilactone B ( ent -I) has also been achieved, as well as that of C-7 epimers of both asperilactones B (8) and C (9).