Evaluating the use of a two-step age-based cutoff for the UICC/AJCC TNM staging system in patients with papillary or follicular thyroid cancer.
Evert F S van VelsenRobin P PeetersMerel T StegengaUwe MäderChristoph ReinersF J van KemenadeTessa M van GinhovenW Edward VisserFrederik Anton VerburgPublished in: European journal of endocrinology (2022)
The optimal two-step age-based cutoff to predict DSS is 45 with 50 years for PTC and 25 with 40 years for FTC, rather than 55 years currently used for DTC. Although these two-step age-based cutoffs were marginally better from a statistical point of view, from a clinical point of view, the recently defined optimal single age cutoffs of 50 years for PTC and 40 years for FTC might be preferable.
Keyphrases