Cooling of the oral mucosa to prevent adverse effects of chemotherapeutic agents: An in vitro study.

Java WalladbegiSarah A SmithAmy K GraysonCraig MurdochMats JontellHelen E Colley

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2018)

This study demonstrates a reduced cytotoxic effect to the TEOM by reducing the temperature of the tissue during chemotherapy treatment and suggests that decreasing the temperature to 20°C could have clinical advantages.

Keyphrases

locally advanced
squamous cell carcinoma
radiation therapy
rectal cancer