Berzosertib (VE-822) inhibits gastric cancer cell proliferation via base excision repair system.

Fubiao NiHengjie TangCheng WangZixiang WangFangyi YuBicheng ChenLinxiao Sun

Published in: Cancer management and research (2019)

We comprehensively analyze the prognostic value of the BER system (UNG, SMUG1, MBD4, TDG, OGG1, MUTYH and NEIL1) based on bioinformatics analysis and experimental confirmation. BER members are associated with distinctive prognostic significance and maybe new valuable prognostic indicators in gastric cancer.

Keyphrases

bioinformatics analysis
cell proliferation
dna repair
cell cycle
pi k akt