Disentangling tau and brain atrophy cluster heterogeneity across the Alzheimer's disease continuum.

Jon B ToledoHangfan LiuMichel J GrotheTanweer RashidLenore LaunerLeslie M ShawHaykel SnoussiSusan HeckbertMichael WeinerJohn Q TrojanwoskiSudha SeshadriMohamad Habesnull null

Published in: Alzheimer's & dementia (New York, N. Y.) (2022)

Each neuroimaging modality captured different aspects of brain aging, genetics, vascular changes, and neurodegeneration leading to individual multimodal phenotyping.

Keyphrases

resting state
white matter
functional connectivity
high throughput
single cell
cognitive decline
cerebrospinal fluid
multiple sclerosis
mild cognitive impairment
subarachnoid hemorrhage