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Effect of microgravity on proliferation and differentiation of embryonic stem cells in an automated culturing system during the TZ-1 space mission.

Xiaohua LeiYujing CaoYing ZhangJingjing QianQian ZhaoFangwu LiuTao ZhangJiaxi ZhouYing GuGuoliang XiaEnkui Duan
Published in: Cell proliferation (2018)
This study demonstrates that space microgravity might play a potential role in supporting 3D cell growth and maintenance of stemness in embryonic stem cells, while it may negatively affect terminal differentiation.
Keyphrases
  • embryonic stem cells
  • stem cells
  • signaling pathway
  • epithelial mesenchymal transition