Characterisation of placental, fetal brain and maternal cardiac structure and function in pre-eclampsia using MRI.
Megan HallAntonio de MarvaoRonny SchweitzerDaniel CrombKathleen ColfordPriya JanduDeclan P O'ReganAlison HoAnthony PriceLucy C ChappellMary A RutherfordLisa StoryPablo LamataJana HutterPublished in: medRxiv : the preprint server for health sciences (2023)
We demonstrate that MRI provides maternal and fetal insights into pre-eclamptic pregnancies that cannot be obtained by other means during pregnancyFunctional placental MRI may be able to differentiate between preeclampsia disease severities, while fetal brain imaging may help refine neurodevelopmental prognostic assessment of children exposed to pre-eclampsia in uteroA specific 3D pattern of left ventricular remodelling and thickening was found to be discriminant of the presence of pre-eclampsia and may provide a basis for improved clinical risk stratification.
Keyphrases
- contrast enhanced
- left ventricular
- pregnancy outcomes
- magnetic resonance imaging
- diffusion weighted imaging
- resting state
- birth weight
- high resolution
- heart failure
- functional connectivity
- young adults
- magnetic resonance
- acute myocardial infarction
- early onset
- cerebral ischemia
- coronary artery disease
- preterm birth
- physical activity
- mass spectrometry
- transcatheter aortic valve replacement
- cardiac resynchronization therapy
- blood brain barrier
- subarachnoid hemorrhage
- congenital heart disease