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Glycemic control target for liver and cardiovascular events risk in metabolic dysfunction-associated steatotic liver disease.

Nobuharu TamakiShun-Ichi WakabayashiTakefumi KimuraYutaka YasuiKaoru TsuchiyaHiroyuki NakanishiDaniel Q HuangTakeji UmemuraMasayuki KurosakiNamiki Izumi
Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2024)
The risk of liver-related events as well as MACE increased in a dose-dependent fashion with an increase in HbA1c levels, except for patients with HbA1c <5.0% for liver-related events. An HbA1c level of 7% was the optimal threshold associated with a lower risk of complications and may be utilized as a target for glycemic control in patients with MASLD.
Keyphrases
  • glycemic control
  • cardiovascular events
  • type diabetes
  • blood glucose
  • weight loss
  • coronary artery disease
  • cardiovascular disease
  • insulin resistance
  • risk factors
  • oxidative stress
  • skeletal muscle