Portable NIV for patients with moderate to severe COPD: two randomized crossover trials.

Daniel Sebastian MajorskiFriederike Sophie MagnetSaadia ThilemannClaudia SchmoorWolfram WindischSarah Bettina Stanzel

Published in: Respiratory research (2021)

The use of a pNIV device during walking can improve dyspnea and walking distance in patients with moderate to severe COPD. Patients who do not already receive long-term NIV therapy are more likely to benefit compared to those undergoing long-term NIV. Careful patient selection is mandatory. Clinical Trial Register: DRKS00013203; DRKS00012913 registered October 20th 2017 and October 16th 2017; https://www.drks.de/drks_web/.

Keyphrases

double blind
open label
clinical trial
chronic obstructive pulmonary disease
placebo controlled
phase ii
lung function
phase iii
high intensity
early onset
lower limb
case report
study protocol
cystic fibrosis
low cost
replacement therapy