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Serum TLR9 and NF-κB Biochemical Markers in Patients with Acute Pancreatitis on Admission.

Erdal Demirtasİlhan KorkmazKıvanç CebecioğluMustafa AyanEsin DemirtaşSefa YurtbayŞeymanur YıldızHüseyin AydınAgnieszka Szarpak
Published in: Emergency medicine international (2020)
We demonstrated that the TLR9 and NF-κB pathway is activated in acute pancreatitis and increases the inflammatory process. This may help to further understand the pathogenesis of disorder, diagnosis, and clinical severity. We proposed that blockage of these inflammatory pathways may play a role in the prevention of the disease progression and development of inflammatory complications.κB levels in patients for the diagnosis and prognostication of AP in the emergency department.
Keyphrases
  • emergency department
  • oxidative stress
  • nuclear factor
  • signaling pathway
  • toll like receptor
  • inflammatory response
  • lps induced
  • immune response
  • pi k akt
  • cell proliferation
  • electronic health record
  • drug induced