Signature mRNA markers in extracellular vesicles for the accurate diagnosis of colorectal cancer.
Byung Seok ChaKyungmoon ParkJun Seok ParkPublished in: Journal of biological engineering (2020)
VEGF and CD133 mRNAs comprise a unique CRC signature in EVs that has the potential to act as a novel, non-invasive, and accurate biomarker that would improve the current diagnostic platform for CRC, while also serving to strengthen the value of EV mRNA as diagnostic markers for myriad of diseases.