The impact of progesterone receptor negativity on oncological outcomes in oestrogen-receptor-positive breast cancer.
Matthew G DaveyÉanna J RyanP J FolanNiamh A O'HalloranMichael R BolandM K BarryK J SweeneyC M MaloneR J McLaughlinM J KerinA J LoweryPublished in: BJS open (2021)
In ER+ disease, PgR- tumours have more aggressive clinicopathological features and worse oncological outcomes. Neoadjuvant and adjuvant therapeutic strategies should be tailored according to PgR status.