The protective effect of L-glutamine against acute Cantharidin-induced Cardiotoxicity in the mice.

Haozhen ShaoLei DongYanyan FengChunhui WangHongxuan Tong

Published in: BMC pharmacology & toxicology (2020)

This study provided evidence that L-glutamine could protect cardiac cells against the acute cantharidin-induced cardiotoxicity and the protective mechanism of glutamine may be related to the myocardial cell membrane or the tricarboxylic acid cycle in the mitochondria.

Keyphrases

drug induced
liver failure
high glucose
diabetic rats
respiratory failure
left ventricular
induced apoptosis
heart failure
adipose tissue
endoplasmic reticulum stress
reactive oxygen species
skeletal muscle
high fat diet induced