Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease.

Manal S Fawzy Baraah T Abu AlSel Eman Ali Toraih

Published in: Journal of clinical laboratory analysis (2020)

Variants and combined genotypes of DICER1 rs3742330, XPO5 rs11077, and RAN rs14035 might be associated with ESRD development in the study population. Integrating molecular analysis in ESRD risk stratification is warranted.

Keyphrases

end stage renal disease
chronic kidney disease
peritoneal dialysis
copy number
gene expression