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The laminin receptor is a receptor for Micropterus salmoides rhabdovirus.

Sheng LuoJiahui LiangGuanjun YangJian-Fei LuJiong Chen
Published in: Journal of virology (2024)
rhabdovirus (MSRV) in largemouth bass, the precise mechanism by which it invades host cells remains unclear. Here, we determined that laminin receptor (LamR) is a novel target of MSRV, that interacts with its G protein and is involved in viral attachment and internalization, transporting with MSRV together in early and late endosomes. This is the first report demonstrating that LamR is a cellular receptor in the MSRV life cycle, thus contributing new insights into host-pathogen interactions.
Keyphrases
  • binding protein
  • life cycle
  • induced apoptosis
  • sars cov
  • oxidative stress
  • cell cycle arrest
  • cell death