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Fast tree aggregation for consensus hierarchical clustering.

Audrey HulotJulien ChiquetFlorence JaffrézicGuillem Rigaill
Published in: BMC bioinformatics (2020)
Our tree aggregation method can be used in conjunction with hierarchical clustering to perform efficient cluster analysis. This approach was found to be robust to the absence of clustering information in some of the data sets as well as an increased variability within true clusters. The method is implemented in R/C++ and available as an R package named mergeTrees, which makes it easy to integrate in existing or new pipelines in several research areas.
Keyphrases
  • single cell
  • rna seq
  • electronic health record
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