CSF ferritin in the clinicopathological progression of Alzheimer's disease and associations with APOE and inflammation biomarkers.

Scott Jonathan AytonShorena JanelidzePawel KalinowskiSebastian PalmqvistAbdel Ali BelaidiErik StomrudAnne RobertsBlaine RobertsOskar HanssonAshley Ian Bush

Published in: Journal of neurology, neurosurgery, and psychiatry (2022)

CSF markers of iron and neuroinflammation have distinct associations with disease stages, while iron may be more intimately associated with apolipoprotein E and tau pathology.

Keyphrases

cognitive decline
iron deficiency
cerebrospinal fluid
high fat diet
type diabetes
adipose tissue
cognitive impairment
lps induced
inflammatory response
subarachnoid hemorrhage
blood brain barrier