Daphnetin: A Novel Anti-Helicobacter pylori Agent.

Genzhu WangJing PangXinxin HuTongying NieXi LuXue LiXiukun WangYun LuXinyi YangJiandong JiangCongran LiYan Q XiongXuefu You

Published in: International journal of molecular sciences (2019)

These results suggested that daphnetin has good activity against MDR H. pylori. The mechanism(s) of daphnetin against H. pylori were related to change of membrane structure, increase of DNA damage and PS translocation, and decrease of H. pylori attachment to GES-1 cells.

Keyphrases

helicobacter pylori
dna damage
induced apoptosis
helicobacter pylori infection
oxidative stress
cell cycle arrest
multidrug resistant
dna repair