A case of mood disorder with severe side effects of antidepressants in association with resistance to thyroid hormone beta with a THRB mutation.

Hazuki Komahashi-SasakiYasui-Furukori NorioRyo MaeharaChie HasegawaKazutaka Shimoda

Published in: Neuropsychopharmacology reports (2022)

Poor tolerability to antidepressants was observed, which may be related to thyroid hormone intolerance. Low doses of quetiapine may contribute to improvements in depression.

Keyphrases

major depressive disorder
bipolar disorder
sleep quality
depressive symptoms
open label
placebo controlled