Indeterminate pediatric acute liver failure is uniquely characterized by a CD103+ CD8+ T-cell infiltrate.

Catherine A ChapinThomas BurnTomas MeijomeKathleen M LoomesHector Melin-AldanaPortia A KreigerPeter F WhitingtonEdward M BehrensEstella M Alonso

Published in: Hepatology (Baltimore, Md.) (2018)

Indeterminate PALF is characterized by a dense CD8+ T-cell hepatic infiltrate consistent with expansion of a tissue resident memory T-cell phenotype; CD8+ T-cells are a biomarker of immune dysregulation in iPALF and may be used to better identify and define this group. (Hepatology 2018).

Keyphrases

liver failure
hepatitis b virus
fine needle aspiration
patient safety
working memory
quality improvement
ultrasound guided
nk cells
respiratory failure
drug induced