In Utero Exposure to Maternal SARS-CoV-2 Infection Is Associated With Higher Left Ventricular Mass in Toddlers.
Mollie W OckeneDuraisamy BalaguruIngrid L MaSamuel C RussoAllison K ArpanteAlexandra CliffordOlyvia J JassetJoon H KimMabel ToribioTakara L StanleyLydia L ShookAndrea G EdlowLindsay T FourmanPublished in: Open forum infectious diseases (2024)
The intrauterine environment plays a critical role in shaping chronic disease risk over the life course. We prospectively evaluated cardiometabolic outcomes in toddlers born to mothers with versus without prenatal severe acute respiratory syndrome coronavirus 2 infection. Children with in utero severe acute respiratory syndrome coronavirus 2 exposure had higher left ventricular mass in association with altered maternal immunologic indices.
Keyphrases
- respiratory syndrome coronavirus
- left ventricular
- sars cov
- birth weight
- coronavirus disease
- gestational age
- hypertrophic cardiomyopathy
- heart failure
- pregnancy outcomes
- acute myocardial infarction
- aortic stenosis
- pregnant women
- mitral valve
- young adults
- left atrial
- low birth weight
- coronary artery disease
- adipose tissue
- physical activity
- aortic valve
- ejection fraction
- preterm infants