Umbilical cord-derived mesenchymal stem cell sheets transplanted subcutaneously enhance cell retention and survival more than dissociated stem cell injections.

Mitsuyoshi NakaoMakoto MatsuiKyungsook KimNobuhiro NishiyamaDavid W GraingerTeruo OkanoHideko KanazawaKenichi Nagase

Published in: Stem cell research & therapy (2023)

hUC-MSC sheet transplantation could be a more effective cell therapeutic approach due to enhanced engraftment and secretion of therapeutic cytokines over injected hUC-MSC suspensions.

Keyphrases

umbilical cord
mesenchymal stem cells
cell therapy
stem cells
single cell
bone marrow
free survival