Differential cognitive and behavioral development from 6 to 24 months in autism and fragile X syndrome.
Lindsay J MullinJoshua RutsohnJulia L GrossKelly E CaravellaRebecca L GrzadzinskiLeigh Anne WeisenfeldLisa FlakeKelly N BotteronStephen R DagerAnnette M EstesJuhi PandeyRobert T SchultzTanya St JohnJason J WolffMark D ShenJoseph PivenHeather C HazlettJessica B GiraultPublished in: Journal of neurodevelopmental disorders (2024)
Our results demonstrate detectable group differences by 6 months between FXS and FH-ASD as well as differential trajectories on each domain throughout infancy. This work further highlights an earlier onset of global cognitive delays in FXS and, conversely, a protracted period of more slowly emerging delays in FH-ASD. Divergent neural and cognitive development in infancy between FXS and FH-ASD contributes to our understanding of important distinctions in the development and behavioral phenotype of these two groups.