Combining method of detection and 70-gene signature for enhanced prognostication of breast cancer.

Josephine M N Lopes Cardozo Marjanka K Schmidt Laura van 't Veer Fatima Cardoso C Poncet Emiel J T Rutgers Caroline A Drukker

Published in: Breast cancer research and treatment (2021)

Among patients with 70-GS high-risk tumors, a significant difference in DMFI was observed between screen-detected and interval cancers, suggesting that method of detection is an additional prognostic factor in this subgroup and should be taken into account when deciding on adjuvant treatment strategies.

Keyphrases

prognostic factors
loop mediated isothermal amplification
real time pcr
label free
early stage
high throughput
copy number
genome wide
gene expression
young adults
sensitive detection
genome wide analysis
breast cancer risk