NMR spectroscopy of lipidic cubic phases.
Sunnia RajputShenggen YaoDavid W KeizerMarc-Antoine SaniFrances SeparovicPublished in: Biophysical reviews (2021)
Lipidic cubic phase (LCP) structures have been used for stabilisation and crystallisation of membrane proteins and show promising properties as drug carriers. In this mini-review, we present how NMR spectroscopy has played a major role in understanding the physico-chemical properties of LCPs and how recent advances in pulsed field gradient NMR techniques open new perspectives in characterising encapsulated molecules.