Login / Signup

FcγRIII in ITP: it ain't over 'til it's over.

Keith R McCrae
Published in: Blood (2016)
In this issue of Blood, Yu et al describe a novel anti–Fcγ receptor III (FcγRIII)-albumin fusion protein that inhibits the development of thrombocytopenia in a murine model of immune thrombocytopenia (ITP).1 The unique aspect of this protein is that it blocks FcγRIII-mediated uptake of antibody-coated platelets without activating FcγRIII and the associated inflammatory response.
Keyphrases
  • inflammatory response
  • immune response
  • red blood cell