The Involvement of Endothelin Pathway in Chronic Psychological Stress-Induced Bladder Hyperalgesia Through Capsaicin-Sensitive C-Fiber Afferents.

Chuying QinYinhuai WangSai LiYuanyuan TangYunliang Gao

Published in: Journal of inflammation research (2022)

The activation of ET-1 receptors could enhance chronic stress-induced bladder hypersensitization and hyperalgesia through capsaicin-sensitive C-fiber afferents. Targeting the endothelin pathway may have therapeutic value for IC/BPS.

Keyphrases

stress induced
spinal cord injury
neuropathic pain
urinary tract
cancer therapy
spinal cord
drug induced
drug delivery
depressive symptoms
physical activity