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Glucocorticoids with low-dose anti-IL1 anakinra rescue in severe non-ICU COVID-19 infection: A cohort study.

Raphael BorieLaurent SavaleAntoine DossierJade GhosnCamille TailléBenoit VisseauxKamel JebreenAbourahmane DialloChloe TesmoingtLise MorerTiphaine GolettoNathalie FaucherLinda HajoujiCatherine NeukirchMathilde PhillipsSandrine StelianidesLila BouadmaSolenn BrosseauSébastien OttavianiJohan PluvyDiane Le PluartMarie-Pierre DebrayAgathe Raynaud-SimonDiane DescampsAntoine KhalilJean Francois TimsitFrancois-Xavier LescureVincent DescampsThomas PapoMarc HumbertBruno CrestaniPhilippe DieudeEric VicautGérard Zalcmannull null
Published in: PloS one (2020)
In COVID-19 non-ICU inpatients at the cytokine release phase, corticosteroids with or without anakinra were associated with a 30% decrease of death risk on Day 15.
Keyphrases
  • low dose
  • intensive care unit
  • coronavirus disease
  • mechanical ventilation
  • sars cov
  • high dose
  • early onset
  • acute respiratory distress syndrome