Platelet Defects in Acute Myeloid Leukemia-Potential for Hemorrhagic Events.
Horia BumbeaAna Maria VladareanuIon DumitruViola Maria PopovCristina CiufuAnca NicolescuMinodora-Cezarina OnisâiCristina MarinescuDiana CisleanuIrina VoicanSinziana SarghiPublished in: Journal of clinical medicine (2021)
The AML patients present changes in adhesion receptors and activation markers, suggesting a functional defect or denatured intracellular signalling in platelets. The exposed data indicate that flow cytometry can effectively identify multiple functional platelet impairments in AML pathogenesis.