Biological Aging Measures Based on Blood DNA Methylation and Risk of Cancer: A Prospective Study.

Pierre-Antoine DuguéJulie K BassettEe Ming WongJiHoon E JooSherly X LiChenglong YuDaniel F SchmidtEnes MakalicNicole Wong DooDaniel D BuchananAllison M HodgeDallas R EnglishJohn L HopperGraham G GilesMelissa C SoutheyRoger L Milne

Published in: JNCI cancer spectrum (2020)

The methylation-based measures PhenoAge and GrimAge may provide insights into the relationship between biological aging and cancer and be useful to predict cancer risk, particularly for lung cancer.

Keyphrases

dna methylation
papillary thyroid
squamous cell
genome wide
gene expression
lymph node metastasis
childhood cancer