A systematic review comparing allogeneic hematopoietic stem cell transplant to gene therapy in sickle cell disease.

Lianne E RotinAuro ViswabandyaRajat KumarChristopher J PatriquinKevin H M Kuo

Published in: Hematology (Amsterdam, Netherlands) (2023)

Reporting of SCD-related complications and patient-important outcomes is lacking for both strategies. We advocate for standardized reporting to better compare outcomes within and between treatment groups.

Keyphrases

hematopoietic stem cell
sickle cell disease
gene therapy
stem cell transplantation
adverse drug
bone marrow
case report
type diabetes
low dose
skeletal muscle
adipose tissue
high dose
insulin resistance
combination therapy
glycemic control