Brain-targeted glycyrrhizic-acid-loaded surface decorated nanoparticles for treatment of cerebral ischaemia and its toxicity assessment.
Niyaz AhmadAbeer M Al-SubaiecRizwan AhmadSonali SharmaMd Aftab AlamMohammad AshafaqRehan Abdur RubFarhan Jalees AhmadPublished in: Artificial cells, nanomedicine, and biotechnology (2019)
CS-coated-GA-loaded-PCL-NPs when administered i.n. enhanced the bioavailability of the drug in rat brain as compared to i.v. administration. The observation from toxicity study concludes; the developed NPS are safe and free of any health associated risk.
Keyphrases
- cancer therapy
- oxide nanoparticles
- drug delivery
- oxidative stress
- healthcare
- public health
- pet ct
- mental health
- cerebral ischemia
- wound healing
- subarachnoid hemorrhage
- health information
- reduced graphene oxide
- emergency department
- blood brain barrier
- gold nanoparticles
- adverse drug
- climate change
- social media
- smoking cessation
- breast cancer risk