Can photobiomodulation therapy be an alternative to pharmacological therapies in decreasing the progression of skeletal muscle impairments of mdx mice?
Shaiane Silva TomazoniHeliodora Leão CasalechiCheila de Sousa Bacelar FerreiraAndrey Jorge SerraHumberto DellêRodrigo Barbosa de Oliveira BritoBrunno Lemes de MeloAdriane Aver VaninNeide Firmo RibeiroAmanda Lima PereiraKadma Karênina Damasceno Soares MonteiroRodrigo Labat MarcosPaulo de Tarso Camillo de CarvalhoLucio FrigoErnesto Cesar Pinto Leal-JuniorPublished in: PloS one (2020)
We believe that the promising and optimistic results about the PBMT in skeletal muscle of mdx mice may in the future contribute to this therapy to be considered a safe alternative for patients with Duchenne Muscular Dystrophy (DMD) in a washout period (between treatment periods with glucocorticoids), allowing them to remain receiving effective and safe treatment in this period, avoiding at this way periods without administration of any treatment.