Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database.

Balachandran KumarendranMichael W O'ReillyKonstantinos N ManolopoulosKonstantinos A ToulisKrishna M GokhaleAlice J SitchChandrika N WijeyaratneArri CoomarasamyWiebke ArltKrishnarajah Nirantharakumar

Published in: PLoS medicine (2018)

We found that women with PCOS have an increased rate of NAFLD. In addition to increased BMI and dysglycemia, androgen excess contributes to the development of NAFLD in women with PCOS. In women with PCOS-related androgen excess, systematic NAFLD screening should be considered.

Keyphrases

polycystic ovary syndrome
primary care
insulin resistance
body mass index
adipose tissue
skeletal muscle
weight gain
general practice
adverse drug
liver fibrosis
weight loss
electronic health record