Subclinical Pulmonary Involvement in Active IBD Responds to Biologic Therapy.

Mark EllrichmannJ BethgeJ BoesenkoetterC ConradR NothT BahmerS NikolausK AdenS ZeissigS Schreiber

Published in: Journal of Crohn's & colitis (2021)

with active IBD present with significant obstructive abnormalities in their PFTs. Obstruction is related to inflammatory activity, with anti-TNF improving PFTs. Pulmonary obstruction and possibly chronic bronchopulmonary inflammation is an overlooked problem in active IBD that is probably obscured by intestinal symptoms.

Keyphrases

rheumatoid arthritis
pulmonary hypertension
oxidative stress
ulcerative colitis
stem cells
sleep quality
depressive symptoms
drug induced
replacement therapy