Germline mutation prevalence in individuals with pancreatic cancer and a history of previous malignancy.

Beth DudleyEve KarloskiFederico A MonzonAatur D SinghiStephen E LincolnNathan BaharyRandall E Brand

Published in: Cancer (2018)

At least 18% of individuals with PC and a personal history of other HBOC- or LS-related cancers carry mutations in a PC susceptibility gene based on our data, suggesting that criteria for genetic testing in individuals with PC should include consideration of previous cancer history. Cancer 2018;124:1691-700. © 2018 American Cancer Society.

Keyphrases

papillary thyroid
squamous cell
gene expression
squamous cell carcinoma
lymph node metastasis
machine learning
dna damage
dna repair
transcription factor
artificial intelligence
data analysis