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Are non-invasive fibrosis markers for chronic hepatitis B reliable in sub-Saharan Africa?

Hailemichael DesalegnHanna AberraNega BerheSvein G GundersenAsgeir Johannessen
Published in: Liver international : official journal of the International Association for the Study of the Liver (2017)
Aspartate aminotransferase to platelet ratio index, FIB-4 and gamma-glutamyl transpeptidase to platelet ratio had good diagnostic properties to detect liver fibrosis and cirrhosis in patients with chronic hepatitis B in East Africa. However, the sensitivity was low, and only 10% of patients with cirrhosis were detected using aspartate aminotransferase to platelet ratio index at the World Health Organization recommended threshold.
Keyphrases
  • liver fibrosis
  • hepatitis b virus