scAAVengr, a transcriptome-based pipeline for quantitative ranking of engineered AAVs with single-cell resolution.

Bilge Esin Ozturk Molly E JohnsonMichael KleymanSerhan TurunçJing HeSara JabalameliZhouhuan XiMeike ViselValérie L DufourSimone IwabeLuis Felipe L Pompeo MarinhoGustavo D AguirreJosé-Alain SahelDavid V SchafferAndreas R PfenningJohn G FlanneryWilliam A BeltranWilliam R Stauffer Leah C Byrne

Published in: eLife (2021)

This work was supported by funding from the Ford Foundation, NEI/NIH, Research to Prevent Blindness, Foundation Fighting Blindness, UPMC Immune Transplant and Therapy Center, and the Van Sloun fund for canine genetic research.

Keyphrases

single cell
rna seq
genome wide
high throughput
health insurance
gene expression
high resolution
single molecule
copy number
dna methylation
stem cells
cell therapy