Technique development of 3D dynamic CS-EPSI for hyperpolarized 13 C pyruvate MR molecular imaging of human prostate cancer.

Hsin-Yu ChenPeder Eric Zufall LarsonJeremy W GordonRobert A BokMarcus FerroneMark van CriekingeLucas CarvajalPeng CaoJohn M PaulyAdam B KerrIlwoo ParkJames B SlaterSarah J NelsonPamela N MunsterRahul AggarwalJohn KurhanewiczDaniel B Vigneron

Published in: Magnetic resonance in medicine (2018)

The results demonstrate the feasibility to characterize prostate cancer metabolism in animals, and now patients using this new 3D dynamic HP MR technique to measure kPL , the kinetic rate constant of [1-13 C]pyruvate to [1-13 C]lactate conversion.

Keyphrases

prostate cancer
end stage renal disease
radical prostatectomy
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
contrast enhanced
prognostic factors
computed tomography