Induction of squamous cell carcinoma after MAP3K8 overexpression in murine salivry gland epithelial cells.

Jun-Han LeeJoseph H JeongTae Hwan KimSo-Yeon KimKyung-Eun KimJe Kyung SeongSang Hyuk Lee

Published in: Head & neck (2019)

MAP3K8 overexpression is associated with SCC development in murine salivary glands. It provides an in vivo framework for the understanding of molecular mechanisms underlying SCC development in the salivary glands and also for the development of a future therapeutic strategy targeting this tumor type.

Keyphrases

squamous cell carcinoma
cell proliferation
transcription factor
radiation therapy
current status
high density
single molecule