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A rare case of childhood mucous membrane pemphigoid involving the oral and genital mucosa.

Katinna E Rodriguez BaisiAshley WentworthAsma J ChatthaDavid J DiCaudoAaron R MangoldSteven A NelsonElaine C SiegfriedCarilyn N WielandMegha Tollefson
Published in: Pediatric dermatology (2021)
Mucous membrane pemphigoid (MMP) is a rare chronic immunobullous disease that involves the mucous membranes and may result in significant scarring and complications if diagnosis is delayed. MMP typically occurs in elderly patients, with very few cases reported in children. Here, we present a 12-year-old female patient with childhood-onset oral and genital MMP, clinically suspected to be lichen sclerosus, but eventually diagnosed as MMP after multiple supportive biopsies and confirmatory direct immunofluorescence. Although treatment was challenging, the combined use of systemic corticosteroids, dapsone, and mycophenolate mofetil was ultimately successful in achieving disease control.
Keyphrases
  • rare case
  • cell migration
  • pulmonary embolism
  • case report
  • risk factors
  • childhood cancer
  • middle aged
  • community dwelling
  • combination therapy