ICG angiography in immediate and delayed autologous breast reconstructions: peroperative evaluation and postoperative outcomes.
Toke AlstrupBekka O ChristensenTine Engberg DamsgaardPublished in: Journal of plastic surgery and hand surgery (2018)
Postoperative complications in patients undergoing autologous breast reconstruction should be kept at the lowest possible level. Optimization of autologous breast reconstruction, especially techniques that can identify tissue perfusion and ischemia, will greatly benefit the patients and consequently society. Hence, the aim of this study was to evaluate the complication rates for autologous pedicle flap breast reconstructions, with and without the use of ICG-angiography. A single-institution retrospective review of mastectomy patients was performed. A total of 230 cases who underwent immediate or delayed, unilateral or bilateral pedicle autologous flap breast reconstruction between January 2013 and September 2016 was reviewed. Complication rates in the ICG-angiography and clinical assessment group were evaluated and compared. A total of 191 cases were identified of which 77 were evaluated with ICG-angiography, and 114 were evaluated clinically. There was no significant difference in overall complication rates between the two groups (ICG-angiography, 36.4%; Clinical assessment, 37.7%; p = .88). No significant difference was observed when stratifying for major or minor complications. However, when stratifying for the timing of the reconstruction, the rate of major complications was significantly lower in the ICG-angiography group (ICG-angiography, 0%; Clinical assessment 23.3%; p = .039). BMI was significantly associated with increased risk of minor complications (p = .018), whereas there was no correlation to age, prior smoking, chemotherapy, radiation, diabetes, or hypertension. Our study found that use of ICG-angiography was associated with a significant decrease in the rate of major complications for immediate autologous reconstructions.
Keyphrases
- breast reconstruction
- optical coherence tomography
- fluorescence imaging
- computed tomography
- bone marrow
- cell therapy
- patients undergoing
- end stage renal disease
- platelet rich plasma
- ejection fraction
- chronic kidney disease
- newly diagnosed
- risk factors
- type diabetes
- photodynamic therapy
- blood pressure
- stem cells
- cardiovascular disease
- body mass index
- magnetic resonance
- adipose tissue
- metabolic syndrome
- patient reported outcomes
- locally advanced
- soft tissue
- glycemic control
- image quality
- weight gain
- weight loss